Tommy Fleetwood claimed his sixth DP World Tour title and a cheque for €1,003,226.95 after winning the 2022 Nedbank Golf Challenge. Here’s the prize money payout for each golfer at the 2022 Nedbank Golf Challenge:
| Position | Player | Prize money | Per shot |
| 1 | Tommy Fleetwood | € 1,003,226.95 | € 3,621.76 |
| 2 | Ryan Fox | € 650,874.07 | € 2,341.27 |
| 3 | Shubhankar Sharma | € 372,906.80 | € 1,336.58 |
| 4 | Richie Ramsay | € 295,584.92 | € 1,055.66 |
| 5 | Christiaan Bezuidenhout | € 229,029.37 | € 815.05 |
| | Sebastian Soderberg | € 229,029.37 | € 815.05 |
| 7 | Gavin Green | € 178,133.96 | € 631.68 |
| 8 | Richard Bland | € 122,149.00 | € 431.62 |
| | Branden Grace | € 122,149.00 | € 431.62 |
| | Rasmus Højgaard | € 122,149.00 | € 431.62 |
| Maximilian Kieffer | € 122,149.00 | € 431.62 | |
| | Min Woo Lee | € 122,149.00 | € 431.62 |
| 13 | Thomas Detry | € 85,641.32 | € 301.55 |
| | Luke Donald | € 85,641.32 | € 301.55 |
| | Ewen Ferguson | € 85,641.32 | € 301.55 |
| | Scott Jamieson | € 85,641.32 | € 301.55 |
| | Thriston Lawrence | € 85,641.32 | € 301.55 |
| | Jordan Smith | € 85,641.32 | € 301.55 |
| 19 | Ross Fisher | € 68,513.06 | € 240.40 |
| | Sam Horsfield | € 68,513.06 | € 240.40 |
| | David Law | € 68,513.06 | € 240.40 |
| | Adrian Otaegui | € 68,513.06 | € 240.40 |
| | Richard Sterne | € 68,513.06 | € 240.40 |
| | Paul Waring | € 68,513.06 | € 240.40 |
| 25 | Lucas Herbert | € 58,872.29 | € 205.85 |
| Yannik Paul | € 58,872.29 | € 205.85 | |
| | Marcel Schneider | € 58,872.29 | € 205.85 |
| | Ashun Wu | € 58,872.29 | € 205.85 |
| 29 | Joakim Lagergren | € 52,657.18 | € 183.47 |
| | Romain Langasque | € 52,657.18 | € 183.47 |
| | Fabrizio Zanotti | € 52,657.18 | € 183.47 |
| 32 | Jorge Campillo | € 46,491.01 | € 161.43 |
| | Robert Macintyre | € 46,491.01 | € 161.43 |
| | Edoardo Molinari | € 46,491.01 | € 161.43 |
| | Antoine Rozner | € 46,491.01 | € 161.43 |
| 36 | Oliver Bekker | € 39,600.55 | € 137.03 |
| | Sean Crocker | € 39,600.55 | € 137.03 |
| | Adrian Meronk | € 39,600.55 | € 137.03 |
| | Dale Whitnell | € 39,600.55 | € 137.03 |
| | Oliver Wilson | € 39,600.55 | € 137.03 |
| 41 | Marcus Armitage | € 34,843.78 | € 120.15 |
| | Rafa Cabrera Bello | € 34,843.78 | € 120.15 |
| | Matthieu Pavon | € 34,843.78 | € 120.15 |
| 44 | George Coetzee | € 30,145.75 | € 103.59 |
| | Matthew Jordan | € 30,145.75 | € 103.59 |
| | Guido Migliozzi | € 30,145.75 | € 103.59 |
| | Thorbjørn Olesen | € 30,145.75 | € 103.59 |
| | Victor Perez | € 30,145.75 | € 103.59 |
| 49 | Shaun Norris | € 25,447.71 | € 87.15 |
| | Eddie Pepperell | € 25,447.71 | € 87.15 |
| 49 | Connor Syme | € 25,447.71 | € 87.15 |
| 52 | Hurly Long | € 21,924.18 | € 74.83 |
| | JC Ritchie | € 21,924.18 | € 74.83 |
| | Justin Walters | € 21,924.18 | € 74.83 |
| 55 | Nicolai Højgaard | € 20,162.41 | € 68.58 |
| 56 | Richard Mansell | € 19,281.53 | € 65.36 |
| | Tapio Pulkkanen | € 19,281.53 | € 65.36 |
| 58 | Wil Besseling | € 17,813.40 | € 60.18 |
| | Kalle Samooja | € 17,813.40 | € 60.18 |
| | Matthew Southgate | € 17,813.40 | € 60.18 |
| 61 | Adri Arnaus | € 16,345.26 | € 55.03 |
| | Haotong Li | € 16,345.26 | € 55.03 |
| 63 | Pablo Larrazábal | € 15,464.38 | € 51.89 |
| 64 | Zander Lombard | € 14,322.49 | € 47.90 |
| | Callum Shinkwin | € 14,322.49 | € 47.90 |
| | Nicolai Von Dellingshausen | € 14,322.49 | € 47.90 |