Tony Finau claimed his fifth PGA Tour title and a cheque for $1,512,000 after winning the 2022 Cadence Bank Houston Open. Here’s the prize money payout for each golfer at the 2022 Cadence Bank Houston Open:
| Position | Player | Prize money | Per shot |
| 1 | Tony Finau | $1,512,000 | $5,727.27 |
| 2 | Tyson Alexander | $915,600 | $3,416.42 |
| 3 | Ben Taylor | $579,600 | $2,154.65 |
| T4 | Trey Mullinax | $353,500 | $1,299.63 |
| T4 | Alex Smalley | $353,500 | $1,299.63 |
| T4 | Alex Noren | $353,500 | $1,299.63 |
| T7 | Adam Hadwin | $273,000 | $1,000.00 |
| T7 | Aaron Rai | $273,000 | $1,000.00 |
| T9 | Scottie Scheffler | $196,500 | $717.15 |
| T9 | Stephan Jaeger | $196,500 | $717.15 |
| T9 | Keith Mitchell | $196,500 | $717.15 |
| T9 | Joseph Bramlett | $196,500 | $717.15 |
| T9 | Joel Dahmen | $196,500 | $717.15 |
| T9 | Gary Woodland | $196,500 | $717.15 |
| T9 | Justin Rose | $196,500 | $717.15 |
| T16 | Jason Day | $123,900 | $450.55 |
| T16 | Ben Griffin | $123,900 | $450.55 |
| T16 | Patrick Rodgers | $123,900 | $450.55 |
| T16 | Mackenzie Hughes | $123,900 | $450.55 |
| T16 | Scott Piercy | $123,900 | $450.55 |
| T16 | Wyndham Clark | $123,900 | $450.55 |
| T22 | David Lipsky | $84,420 | $305.87 |
| T22 | Martin Laird | $84,420 | $305.87 |
| T22 | Aaron Wise | $84,420 | $305.87 |
| T22 | Sahith Theegala | $84,420 | $305.87 |
| 26 | Callum Tarren | $67,620 | $244.12 |
| T27 | Maverick McNealy | $56,332 | $202.63 |
| T27 | Kyle Westmoreland | $56,332 | $202.63 |
| T27 | Cole Hammer | $56,332 | $202.63 |
| T27 | Ryan Armour | $56,332 | $202.63 |
| T27 | Davis Riley | $56,332 | $202.63 |
| T27 | Austin Cook | $56,332 | $202.63 |
| T27 | James Hahn | $56,332 | $202.63 |
| T27 | Russell Knox | $56,332 | $202.63 |
| T35 | Andrew Putnam | $42,735 | $153.17 |
| T35 | Eric Cole | $42,735 | $153.17 |
| T35 | Carl Yuan | $42,735 | $153.17 |
| T35 | Si Woo Kim | $42,735 | $153.17 |
| T39 | Travis Vick (a) | $0 | $0.00 |
| T39 | Harris English | $36,540 | $130.50 |
| T39 | Harry Hall | $36,540 | $130.50 |
| T39 | Adam Svensson | $36,540 | $130.50 |
| T43 | Erik Barnes | $30,660 | $109.11 |
| T43 | Kevin Tway | $30,660 | $109.11 |
| T43 | Will Gordon | $30,660 | $109.11 |
| T43 | Davis Thompson | $30,660 | $109.11 |
| T47 | Justin Suh | $23,705 | $84.06 |
| T47 | Michael Kim | $23,705 | $84.06 |
| T47 | Seonghyeon Kim | $23,705 | $84.06 |
| T47 | Francesco Molinari | $23,705 | $84.06 |
| T47 | Zack Fischer | $23,705 | $84.06 |
| 52 | Robby Shelton | $21,084 | $74.50 |
| T53 | Denny McCarthy | $20,118 | $70.84 |
| T53 | Byeong Hun An | $20,118 | $70.84 |
| T53 | Nick Watney | $20,118 | $70.84 |
| T53 | Matthew NeSmith | $20,118 | $70.84 |
| T57 | Luke List | $19,236 | $67.49 |
| T57 | Sam Stevens | $19,236 | $67.49 |
| T57 | Zach Johnson | $19,236 | $67.49 |
| T57 | Stewart Cink | $19,236 | $67.49 |
| T57 | Taylor Montgomery | $19,236 | $67.49 |
| T62 | Brandon Wu | $18,648 | $65.20 |
| T62 | Paul Haley II | $18,648 | $65.20 |
| T64 | Seung-Yul Noh | $18,312 | $63.80 |
| T64 | Matthias Schwab | $18,312 | $63.80 |
| 66 | Taylor Pendrith | $18,060 | $62.71 |
| 67 | Max McGreevy | $17,892 | $61.48 |
| 68 | Zecheng Dou | $17,724 | $60.49 |