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Rory McIlroy claimed his 21st PGA Tour title and a cheque for $1,566,000 after winning the 2022 RBC Canadian Open. Here’s the prize money payout for each golfer at the 2022 RBC Canadian Open:
| Position | Player | Prize money | Per shot |
| 1 | Rory McIlroy | $1,566,000 | $6,000 |
| 2 | Tony Finau | $948,300 | $3,606 |
| 3 | Justin Thomas | $600,300 | $2,265 |
| T4 | Justin Rose | $391,500 | $1,472 |
| T4 | Sam Burns | $391,500 | $1,472 |
| 6 | Corey Conners | $315,375 | $1,177 |
| T7 | Keith Mitchell | $273,325 | $1,012 |
| T7 | Chris Kirk | $273,325 | $1,012 |
| T7 | Wyndham Clark | $273,325 | $1,012 |
| T10 | Danny Lee | $219,675 | $811 |
| T10 | Shane Lowry | $219,675 | $811 |
| T10 | Matt Fitzpatrick | $219,675 | $811 |
| T13 | Kelly Kraft | $160,515 | $590 |
| T13 | Brendon Todd | $160,515 | $590 |
| T13 | Aaron Rai | $160,515 | $590 |
| T13 | Harold Varner III | $160,515 | $590 |
| T13 | Austin Cook | $160,515 | $590 |
| T18 | Patrick Rodgers | $123,975 | $454 |
| T18 | Scottie Scheffler | $123,975 | $454 |
| T18 | Doug Ghim | $123,975 | $454 |
| T21 | Adam Svensson | $94,830 | $346 |
| T21 | Scott Piercy | $94,830 | $346 |
| T21 | Adam Long | $94,830 | $346 |
| T21 | Alex Smalley | $94,830 | $346 |
| T25 | John Huh | $71,485 | $260 |
| T25 | Jim Knous | $71,485 | $260 |
| T25 | Sebastián Muñoz | $71,485 | $260 |
| T28 | Mackenzie Hughes | $57,047 | $207 |
| T28 | Emiliano Grillo | $57,047 | $207 |
| T28 | Hank Lebioda | $57,047 | $207 |
| T28 | Chase Seiffert | $57,047 | $207 |
| T28 | Danny Willett | $57,047 | $207 |
| T28 | Jonas Blixt | $57,047 | $207 |
| T28 | Nick Taylor | $57,047 | $207 |
| T35 | Adam Hadwin | $39,730 | $143 |
| T35 | Justin Lower | $39,730 | $143 |
| T35 | Vince Whaley | $39,730 | $143 |
| T35 | Seung-Yul Noh | $39,730 | $143 |
| T35 | Charley Hoffman | $39,730 | $143 |
| T35 | Ryan Moore | $39,730 | $143 |
| T35 | Matt Wallace | $39,730 | $143 |
| T35 | Ryan Armour | $39,730 | $143 |
| T35 | Nick Hardy | $39,730 | $143 |
| T44 | Austin Smotherman | $30,015 | $108 |
| T44 | Mark Hubbard | $30,015 | $108 |
| T46 | Carlos Ortiz | $26,535 | $95 |
| T46 | Paul Barjon | $26,535 | $95 |
| T48 | Cameron Smith | $22,568 | $81 |
| T48 | Brandt Snedeker | $22,568 | $81 |
| T48 | Aaron Cockerill | $22,568 | $81 |
| T48 | Vaughn Taylor | $22,568 | $81 |
| T48 | Lee Hodges | $22,568 | $81 |
| T53 | Sahith Theegala | $20,387 | $73 |
| T53 | Brett Drewitt | $20,387 | $73 |
| T53 | Robert Streb | $20,387 | $73 |
| T53 | Ben Martin | $20,387 | $73 |
| T53 | Jhonattan Vegas | $20,387 | $73 |
| T53 | Bo Van Pelt | $20,387 | $73 |
| T59 | Cameron Percy | $19,662 | $70 |
| T59 | J.J. Henry | $19,662 | $70 |
| T61 | Dylan Frittelli | $19,314 | $68 |
| T61 | Kramer Hickok | $19,314 | $68 |
| 63 | Ben Crane | $19,053 | $67 |
| T64 | Sean O’Hair | $18,531 | $65 |
| T64 | Rafa Cabrera Bello | $18,531 | $65 |
| T64 | David Skinns | $18,531 | $65 |
| T64 | Andrew Novak | $18,531 | $65 |
| T64 | Brandon Hagy | $18,531 | $65 |
| 69 | Trey Mullinax | $18,009 | $63 |
| 70 | Dawie van der Walt | $17,835 | $62 |