Hudson Swafford claimed his third PGA Tour title and a cheque for $1,368,000 after winning the 2022 The American Express. Here’s the prize money payout for each golfer at the 2022 The American Express:
| Position | Players | Prize money | Per shot |
| 1 | Hudson Swafford | $1,368,000 | $5,162.26 |
| 2 | Tom Hoge | $828,400 | $3,102.62 |
| T3 | Lanto Griffin | $402,800 | $1,502.99 |
| T3 | Brian Harman | $402,800 | $1,502.99 |
| T3 | Lee Hodges | $402,800 | $1,502.99 |
| T6 | Denny McCarthy | $256,500 | $953.53 |
| T6 | Francesco Molinari | $256,500 | $953.53 |
| T6 | Will Zalatoris | $256,500 | $953.53 |
| 9 | Patrick Cantlay | $222,300 | $823.33 |
| 10 | Paul Barjon | $207,100 | $764.21 |
| T11 | Sungjae Im | $184,300 | $677.57 |
| T11 | Si Woo Kim | $184,300 | $677.57 |
| 13 | Wyndham Clark | $161,500 | $591.58 |
| T14 | Russell Henley | $119,700 | $436.86 |
| T14 | Zach Johnson | $119,700 | $436.86 |
| T14 | David Lipsky | $119,700 | $436.86 |
| T14 | Seamus Power | $119,700 | $436.86 |
| T14 | Andrew Putnam | $119,700 | $436.86 |
| T14 | Jon Rahm | $119,700 | $436.86 |
| T14 | Roger Sloan | $119,700 | $436.86 |
| T14 | Brandt Snedeker | $119,700 | $436.86 |
| T22 | Patton Kizzire | $79,420 | $288.80 |
| T22 | Luke List | $79,420 | $288.80 |
| T22 | Harold Varner III | $79,420 | $288.80 |
| T25 | Adam Hadwin | $55,955 | $202.74 |
| T25 | Charles Howell III | $55,955 | $202.74 |
| T25 | J.T. Poston | $55,955 | $202.74 |
| T25 | Scottie Scheffler | $55,955 | $202.74 |
| T25 | Greyson Sigg | $55,955 | $202.74 |
| T25 | Alex Smalley | $55,955 | $202.74 |
| T25 | J.J. Spaun | $55,955 | $202.74 |
| T25 | Stephen Stallings Jr. | $55,955 | $202.74 |
| T33 | Joseph Bramlett | $39,683 | $143.26 |
| T33 | Lucas Glover | $39,683 | $143.26 |
| T33 | Justin Rose | $39,683 | $143.26 |
| T33 | Nick Taylor | $39,683 | $143.26 |
| T33 | Sahith Theegala | $39,683 | $143.26 |
| T33 | Camilo Villegas | $39,683 | $143.26 |
| T33 | Jared Wolfe | $39,683 | $143.26 |
| T40 | Abraham Ancer | $27,014 | $97.17 |
| T40 | Christiaan Bezuidenhout | $27,014 | $97.17 |
| T40 | Jason Dufner | $27,014 | $97.17 |
| T40 | Tony Finau | $27,014 | $97.17 |
| T40 | Harry Higgs | $27,014 | $97.17 |
| T40 | Graeme McDowell | $27,014 | $97.17 |
| T40 | Patrick Rodgers | $27,014 | $97.17 |
| T40 | Vincent Whaley | $27,014 | $97.17 |
| T40 | Cameron Young | $27,014 | $97.17 |
| T49 | Bronson Burgoon | $18,949 | $67.92 |
| T49 | Jason Day | $18,949 | $67.92 |
| T49 | Hank Lebioda | $18,949 | $67.92 |
| T49 | Sam Ryder | $18,949 | $67.92 |
| T49 | Sepp Straka | $18,949 | $67.92 |
| T49 | Adam Svensson | $18,949 | $67.92 |
| T55 | Kevin Chappell | $17,632 | $62.97 |
| T55 | Michael Gligic | $17,632 | $62.97 |
| T55 | Patrick Reed | $17,632 | $62.97 |
| T55 | Martin Trainer | $17,632 | $62.97 |
| T59 | Doug Ghim | $17,024 | $60.58 |
| T59 | Trey Mullinax | $17,024 | $60.58 |
| T59 | Aaron Rai | $17,024 | $60.58 |
| T59 | Davis Riley | $17,024 | $60.58 |
| T63 | Emiliano Grillo | $16,492 | $58.48 |
| T63 | K.H. Lee | $16,492 | $58.48 |
| T63 | Henrik Norlander | $16,492 | $58.48 |
| 66 | Anirban Lahiri | $16,188 | $57.20 |
| T67 | Nick Hardy | $15,884 | $55.93 |
| T67 | Taylor Moore | $15,884 | $55.93 |
| T67 | Seung Yul Noh | $15,884 | $55.93 |
| 70 | Brice Garnett | $15,580 | $54.67 |
