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Will Zalatoris claimed his maiden PGA Tour title and a cheque for $2,700,000 after winning the 2022 FedEx St. Jude Championship. Here’s the prize money payout for each golfer at the 2022 FedEx St. Jude Championship:
| Position | Player | Prize money | Per shot |
| T1 | Will Zalatoris | $2,700,000 | $10,188.68 |
| T1 | Sepp Straka | $1,635,000 | $6,169.81 |
| T3 | Lucas Glover | $885,000 | $3,302.24 |
| T3 | Brian Harman | $885,000 | $3,302.24 |
| T5 | Jon Rahm | $480,000 | $1,784.39 |
| T5 | Adam Scott | $480,000 | $1,784.39 |
| T5 | Collin Morikawa | $480,000 | $1,784.39 |
| T5 | Tony Finau | $480,000 | $1,784.39 |
| T5 | Matthew Fitzpatrick | $480,000 | $1,784.39 |
| T5 | Andrew Putnam | $480,000 | $1,784.39 |
| T5 | Trey Mullinax | $480,000 | $1,784.39 |
| 12 | Sungjae Im | $348,750 | $1,291.67 |
| T13 | Lee Hodges | $260,893 | $962.70 |
| T13 | Cameron Davis | $260,893 | $962.70 |
| T13 | Justin Thomas | $260,893 | $962.70 |
| T13 | Tom Kim | $260,893 | $962.70 |
| T13 | Joaquin Niemann | $260,893 | $962.70 |
| T13 | Sahith Theegala | $260,893 | $962.70 |
| T13 | Cameron Smith | $260,893 | $962.70 |
| T20 | Viktor Hovland | $152,813 | $561.81 |
| T20 | J.T. Poston | $152,813 | $561.81 |
| T20 | Kevin Kisner | $152,813 | $561.81 |
| T20 | Dylan Frittelli | $152,813 | $561.81 |
| T20 | K-H Lee | $152,813 | $561.81 |
| T20 | Denny McCarthy | $152,813 | $561.81 |
| T20 | Sam Burns | $152,813 | $561.81 |
| T20 | Ryan Palmer | $152,813 | $561.81 |
| T28 | Corey Conners | $107,250 | $392.86 |
| T28 | Wyndham Clark | $107,250 | $392.86 |
| T28 | Troy Merritt | $107,250 | $392.86 |
| T31 | Maverick McNealy | $78,886 | $287.91 |
| T31 | Cameron Young | $78,886 | $287.91 |
| T31 | Aaron Wise | $78,886 | $287.91 |
| T31 | Taylor Moore | $78,886 | $287.91 |
| T31 | Emiliano Grillo | $78,886 | $287.91 |
| T31 | Michael Thompson | $78,886 | $287.91 |
| T31 | Tyrrell Hatton | $78,886 | $287.91 |
| T31 | Keith Mitchell | $78,886 | $287.91 |
| T31 | Davis Riley | $78,886 | $287.91 |
| T31 | Adam Schenk | $78,886 | $287.91 |
| T31 | Tyler Duncan | $78,886 | $287.91 |
| T42 | Si Woo Kim | $54,750 | $199.09 |
| T42 | Mito Pereira | $54,750 | $199.09 |
| T42 | Max Homa | $54,750 | $199.09 |
| T42 | J.J. Spaun | $54,750 | $199.09 |
| T46 | Mackenzie Hughes | $42,330 | $153.37 |
| T46 | Stephan Jaeger | $42,330 | $153.37 |
| T46 | Shane Lowry | $42,330 | $153.37 |
| T46 | Sebastian Munoz | $42,330 | $153.37 |
| T46 | David Lipsky | $42,330 | $153.37 |
| T51 | Gary Woodland | $36,050 | $130.14 |
| T51 | Aaron Rai | $36,050 | $130.14 |
| T51 | Robert Streb | $36,050 | $130.14 |
| T51 | Chez Reavie | $36,050 | $130.14 |
| T51 | Sam Ryder | $36,050 | $130.14 |
| T51 | Adam Svensson | $36,050 | $130.14 |
| T57 | Beau Hossler | $34,200 | $123.02 |
| T57 | Xander Schauffele | $34,200 | $123.02 |
| T57 | Patrick Cantlay | $34,200 | $123.02 |
| T57 | Martin Laird | $34,200 | $123.02 |
| T61 | Greyson Sigg | $33,150 | $118.82 |
| T61 | James Hahn | $33,150 | $118.82 |
| T61 | Hayden Buckley | $33,150 | $118.82 |
| T64 | Marc Leishman | $32,250 | $114.77 |
| T64 | Christiaan Bezuidenhout | $32,250 | $114.77 |
| T64 | Rickie Fowler | $32,250 | $114.77 |
| 67 | Brendon Todd | $31,650 | $112.23 |
| 68 | Taylor Pendrith | $31,350 | $110.78 |
| 69 | Adam Hadwin | $31,050 | $107.44 |